CYP4B1 allele nomenclature

Allele

Protein

Nucleotide changes,
cDNA

Effect

Enzyme activity

References

In_vivo

In_vitro

CYP4B1*1

CYP4B1.1

None

None

Normal

Normal

 

CYP4B1*2A

 

881_882delAT; 993G>A
1018C>T; 1123C>T

294Frameshift

 

 

Lo-Guidice et al, 2002

CYP4B1*2B

 

881_882delAT; 993G>A; 1018C>T

294Frameshift

 

 

Hiratsuka et al., 2004

CYP4B1*3

CYP4B1.3

517C>T

R173W

 

 

Lo-Guidice et al, 2002

CYP4B1*4

CYP4B1.4

964A>G

S322G

 

 

Lo-Guidice et al, 2002

CYP4B1*5

CYP4B1.5

993G>A

M331I

 

 

Lo-Guidice et al, 2002

CYP4B1*6

CYP4B1.6

517C>T; 1033G>A

R173W; V345I

 

 

Hiratsuka et al., 2004

CYP4B1*7

See CYP4B1*2B 

  

  

Changes made since the last update (13-Nov-2007) are marked in red.

Links to the NCBI dbSNP homepage are available for functional SNPs when present in NCBI's database.

Nucleotide variations in bold are the major SNPs/alterations responsible for the phenotype of the corresponding allele.

Please contact Dr. Jean-Marc Lo-Guidice for more information about CYP4B1*2, *3, *4 and *5 alleles. 

OMIM GeneCards

 

 


Home Page Inclusion criteria
CYP1A1 CYP1A2 CYP1B1 CYP2A6 CYP2A13 CYP2B6 CYP2C8 CYP2C9 CYP2C19 CYP2D6 CYP2E1 CYP2F1 CYP2J2
CYP2R1 CYP2S1 CYP2W1 CYP3A4 CYP3A5 CYP3A7 CYP3A43 CYP4A11 CYP4A22 CYP4B1 CYP4F2 CYP5A1 CYP8A1 CYP19A1 CYP21A2 CYP26A1 POR

This page was updated 10-Dec-2007 by Sarah C Sim
Questions and comments are always welcome