The Human Cytochrome P450 (CYP) Allele Nomenclature Database 

 

Allele nomenclature for Cytochrome P450 enzymes

 


Inclusion criteria - New criteria regarding variants identified by NGS

 

Cytochrome P450 Oxidoreductase:
POR

CYP1 family:    
CYP1A1; CYP1A2; CYP1B1

CYP2 family:
CYP2A6; CYP2A13; CYP2B6; CYP2C8; CYP2C9; CYP2C19; CYP2D6; CYP2E1; CYP2F1; CYP2J2; CYP2R1; CYP2S1; CYP2W1

CYP3 family:        
CYP3A4; CYP3A5; CYP3A7; CYP3A43

CYP4 family: 
CYP4A11; CYP4A22; CYP4B1; CYP4F2

CYP>4 families:
CYP5A1; CYP8A1; CYP19A1; CYP21A2; CYP26A1

SNP information on CYP17A1 can be found
here

 

 

 

The Human Cytochrome P450 (CYP) Allele Nomenclature Committee

 

 

Webmaster
Sarah C Sim

Associate Webmaster for CYP2D6
Andrea Gaedigk
 

Editors
Magnus Ingelman-Sundberg
Ann K Daly
Daniel W Nebert

Advisory Board
Jürgen Brockmöller
Michel Eichelbaum
Seymour Garte
Joyce A Goldstein
Frank J Gonzalez
Fred F Kadlubar
Tetsuya Kamataki
Urs A Meyer
David R Nelson
Michael R Waterman
Anna Wedell
Ulrich M Zanger

 

 

Useful links
David Nelson's homepage for cytochrome P450 nomenclature
David Flockhart’s Cytochrome P450 Drug Interaction Table
Kirill N. Degtyarenko's Directory of P450-containing Systems
Cytochrome P450 Knowledgebase
Recommendations for a Nomenclature System for Human Gene Mutations
dbSNP at NCBI
PharmGKB
The NIEHS SNPs Program
GeneSNPs at the Utah Genome Center
The JSNP database
The HGVbase
NCI's SNP500Cancer site
Genome-Wide Association Studies